大气与环境光学学报 ›› 2017, Vol. 12 ›› Issue (3): 161-168.

• 综述 •    下一篇

量子点标记荧光分析技术在痕量小分子有机污染物检测中的应用

曲海波1, 赵苏春2, 王志刚1*   

  1. ( 1 扬州大学 环境科学与工程学院,江苏 扬州,225127; 
    2 扬州市环境监测中心站,江苏 扬州, 225009 )
  • 出版日期:2017-05-28 发布日期:2017-05-18
  • 通讯作者: 王志刚,(1981-),男,江苏仪征人,博士,江苏仪征人,博士,研究生导师,主要从事先进环境分析监测方法与技术方面的研究。 E-mail:wangzg@yzu.edu.cn
  • 作者简介:曲海波,(1989-),男,山东潍坊人,硕士研究生,山东潍坊人,主要从事痕量环境污染物荧光免疫分析方面的研究。
  • 基金资助:

    Supported by Natural Science Foundation of the Jiangsu Higher Education Institutions of China(江苏省环境材料与工程重点实验室开放基金, 13KJB610017), Foundation of Jiangsu Key Laboratory of environmental materials and environmental engineering(江苏省环境材料与工程重点实验室开放基金)

Application of Quantum Dots Fluorescence Analysis Technology in the Detection of Trace Small Molecular Organic Pollutants

QU Haibo1, ZHAO Suchun2, WANG Zhigang1*   

  1. (1 College of Environmental Science and Engineering, Yangzhou University, Yangzhou 225127, China; 
    2 Yangzhou Environmental Monitoring Center, Yangzhou 225009, China)
  • Published:2017-05-28 Online:2017-05-18

摘要:

量子点是一种半导体纳米粒子,具有荧光量子产率高、激发光谱宽、发射光谱窄而可调、耐光漂白等独特的光学特性,在健康、食品安全、医药卫生、环境分析等诸多领域得到了广泛应用。简述了量子点的基本特性,针对近年来量子点荧光分析在痕量小分子有机污染物检测中的应用技术研究,从量子点标记荧光免疫吸附分析(QDs-FLISA)技术、荧光共振能量转移(FRET)技术、免疫传感器技术三个方面进行了综述。最后,就该研究领域存在的问题和发展方向提出了看法。

关键词: 量子点, 小分子有机污染物, 荧光免疫分析, 环境分析

Abstract:

Quantum dot is a kind of semiconductor nanoparticles, which has the unique optical properties of high fluorescence quantum yield, wide excitation spectrum, narrow emission spectrum, adjustable emission wavelength and anti-photobleaching. In recent years, it has been widely used in the area of health, food security, medicine, health care and environmental analysis. The basic features of quantum dots are briefly described, and the studies of small molecules trace organic pollutants analysis are reviewed based on quantum dot fluorescent technology including fluorescence linked immunosorbent assay, fluorescence resonance energy transfer (FRET) technology,and immune sensor technology. Finally, some existing problems and development direction in the field are presented.

Key words: quantum dots, small molecule organic pollutants, fluoroimmunoassay, environmental analysis

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